Home > alternative medicine, National Center for Complementary and Alternative Medicine > S-Adenosyl-L-Methionine (SAMe): An Introduction

S-Adenosyl-L-Methionine (SAMe): An Introduction

October 31, 2012

S-Adenosyl-L-Methionine (SAMe): An Introduction

Source: National Center for Complementary and Alternative Medicine (NCCAM)

S-Adenosyl-L-methionine (also called S-adenosyl methionine, S-adenosylmethionine, SAMe, or SAM-e in the United States or ademetionine in Europe, and also often abbreviated as SAM and AdoMet) is a chemical that is found naturally in the body. SAMe is sold in the United States as a dietary supplement. This fact sheet provides basic information about SAMe, summarizes scientific research on safety and effectiveness, and suggests sources for additional information.

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